Author	Year	Surgical specialty	Regime	Results
Ausen K⁠[@141087]	2015	Plastic surgery: reduction mammoplasty	Wound moistened with 20 mL of TXA (25 mg/mL) before wound closure	Significant reduction in drain fluid production
Ausen K[@141078]	2019	Plastic surgery: body contouring	Bolus of 200mL (5 mg/mL) into wound cavity post wound closure (via drainage tubes) Moistening wound surface with 20 mL of TXA (25 mg/mL) prior to wound closure	Peak serum concentration approximately 5 µg/mL
Ausen K[@141088]	2020	Oncologic breast	Wound moistening with 20 mL of TXA (25 mg/mL) before wound closure	Significant reduction in drain production and earlier removal of drain Increased rate of seroma aspiration in those undergoing lymph node clearance, but no increase in chronic seroma