Variable Cephazolin or cephalexin
(n = 190)
Piperacillin and tazobactam
(n = 15)
p value
Age (years): mean ± standard deviation 45.3 ± 17.8 58.3 ± 19.6 0.02
Male: n patients (%) 124 (65) 10 (67) 0.91
Diabetes: n patients (%) 10 (5) 2 (13) 0.20
% TBSA: median, IQR 5 (2–10) 4 (2–5) 0.50
% TBSA debrided at first operation: median, IQR 4 (1–8) 3 (1.8–5) 0.67
High risk location of burn (face/hand/foot/ perineum): n patients (%) 110 (58) 9 (60) 0.87
Days post injury: median, IQR 2 (1–5) 5 (2.5–10) 0.06
Positive preoperative wound swab: n patients (%) 49 (26) 7 (47) 0.08
Duration of antibiotics: mean ± standard deviation 3.9 ± 2.2 5.0 ± 3.0 0.19