Biodegradable temporising matrix for necrotising soft tissue infections: a case report

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Sadhishaan Sreedharan
Edwin Morrison
Heather Cleland
Sophie Ricketts
Frank Bruscino-Raiola


Biodegradable Temporising Matrix, Necrotising fasciitis, Synthetic dermal matrix, Necrotising soft tissue infections


Necrotising soft tissue infection (NSTI) is a rapidly progressing disease that presents a surgical emergency. Timely antibiotics, radical debridement of infected tissues and adjuvant hyperbaric oxygen therapy are the foundations of its treatment. Split-skin graft (SSG) is the main reconstruction technique due to its simplicity and dependability. Dermal substitutes, as well as creating a suitable wound bed for grafting, aim to recreate the inherent thickness and pliability of skin. One innovation, Novosorb™ (produced by PolyNovo Ltd, Port Melbourne, Australia), is a biodegradable temporising matrix (BTM) that is an entirely synthetic implantable dermal matrix that creates a neo-dermis in complex wounds. 

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